$90.00
Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree, native to central and western Africa. As a selective alpha-2 adrenergic receptor antagonist, it works by blocking the receptors responsible for inhibiting fat breakdown. This blockade elevates norepinephrine levels, stimulating lipolysis and mobilizing stored fatty acids as fuel. Yohimbine crosses the blood-brain barrier, producing both central and peripheral effects on the sympathetic nervous system. Each tablet contains 10 mg of yohimbine HCl. For laboratory research use only.
Yohimbine's primary area of research interest is its ability to enhance lipolysis by blocking alpha-2 adrenergic receptors in fat cells, particularly in stubborn adipose tissue where these receptors are highly concentrated. By elevating norepinephrine, it promotes fatty acid mobilization during fasted states and exercise. Research indicates improved peripheral circulation and oxygen delivery to tissue, increased energy expenditure, reduced fatigue, and enhanced endurance during physical activity. Studies using 0.2 mg/kg body weight have demonstrated increased fat oxidation without significant cardiovascular disruption in healthy subjects. At 10 mg per tablet, dosing is straightforward to titrate across research protocols. Its stimulatory effects on the sympathetic nervous system may also support motivation and exercise capacity.
These ranges are general, research-use suggestions to help you prepare your peptides. This calculator and recommended doses are not medical advice. Start low, assess tolerance, and adjust cautiously.
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Blocks alpha-2 adrenergic receptors to support lipolysis, especially in stubborn fat areas.
Commonly researched in a fasted state, with simple oral dosing that can be split through the day.
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Dynamic Pharmaceuticals Yohimbine contains 50 tablets of 10mg Yohimbine (per tablet).
Yohimbine may cause anxiety, nervousness, elevated heart rate, and increased blood pressure due to its sympathomimetic activity. Other reported effects include insomnia, dizziness, headache, tremors, increased urinary frequency, and gastrointestinal symptoms such as nausea or diarrhea. Risk of adverse effects increases at doses exceeding two tablets (20 mg) daily. Yohimbine is contraindicated in subjects with renal or hepatic dysfunction, cardiovascular conditions, or a history of psychiatric disorders. It should not be combined with MAOIs, tricyclic antidepressants, or other stimulatory compounds without caution. For research use only.
Research protocols begin with half a tablet or one 10 mg tablet daily to assess tolerance, taken in a fasted state. If well tolerated, dosage may be increased to two 10 mg tablets per day, split into two separate administrations. For a 70 kg subject, 0.2 mg/kg body weight equates to approximately 14 mg daily, placing one tablet at 10 mg and one and a half tablets at 15 mg as practical reference points. Tablets should be taken between meals or before fasted exercise to maximize lipolytic activity. Do not exceed two tablets (20 mg) daily in research settings without documented tolerability. Avoid combining with other stimulatory compounds. For laboratory research use only.
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