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SS-31 (Elamipretide) is a synthetic peptide designed to support mitochondrial function by targeting cardiolipin, a lipid found in the inner mitochondrial membrane. Rather than acting on receptors or signaling pathways, it works directly at the mitochondrial level to help stabilize membrane structure, positioning it as a option for research into cellular energy production and oxidative stress.
SS-31's primary research application is mitochondrial support and oxidative stress reduction. It binds to cardiolipin, helping stabilize the inner mitochondrial membrane and supporting more efficient ATP production while reducing the formation of reactive oxygen species. Unlike peptides that act through hormonal or receptor-based pathways, SS-31 works directly at the organelle level, making it relevant for research into cellular aging, exercise capacity, and conditions linked to mitochondrial dysfunction. This distinguishes it from broader metabolic peptides and positions it as a option for cellular-energy-focused research.
These ranges are general, research-use suggestions to help you prepare your peptides. This calculator and recommended doses are not medical advice. Start low, assess tolerance, and adjust cautiously.
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A mitochondria-targeted peptide researched for cellular energy support, oxidative stress reduction, and membrane stabilization.
Targets cardiolipin in the inner mitochondrial membrane; Supports ATP production and reduced oxidative damage; Compatible with NAD+, Epitalon, and MOTS-c stacks.
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One vial of SS-31 contains 10mg of peptide. Strictly intended for laboratory research purposes only.
SS-31 is generally well-tolerated across available research. The most commonly reported effect is mild redness, itching, or irritation at the injection site. Systemic side effects appear to be limited, though research on long-term use remains ongoing. As with any peptide affecting cellular energy pathways, individuals with existing mitochondrial or metabolic conditions should consult a medical professional before use.
SS-31 is typically dosed at 2-5 mg per injection, administered subcutaneously, with frequency varying by research protocol from once daily to several times per week. Effects on energy and recovery are generally studied over weeks rather than assessed acutely. Individual response varies, and some research protocols adjust dosing frequency based on the specific application under study. No loading phase is required.
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